An immuno-oncology targeting panel accurately characterized tumor-resident immune cells and located pathologically and clinically relevant tumor microenvironment features. Molecular-Level Dissection ...

Mammalian genomes have been colonised by transposable elements (TEs), so called ‘genetic parasites’, which occupy ~ 50% of genomic DNA and harbour the potential to propagate, resulting in genetic ...

Most lethal mutations in wild fruit flies are driven by newly transferred jumping genes, not small DNA errors, according to a new study from Duke University. The findings, published in PLOS Biology, ...

Transposable elements have proliferated in the bacterium Enterococcus faecium, altering its metabolism and genome structure.

Researchers from UNSW Sydney have discovered that a particular transposable element, or jumping gene, in the genome has a profound effect on the immune response to virus infection. The findings in ...

To understand how organisms are related, researchers use molecular information to construct phylogenetic trees. Most of the time, scientists use thousands of protein-coding sequences to determine ...

Researchers from the University of New South Wales (UNSW) Sydney report they have discovered that a particular transposable element in the genome has an effect on the immune response to virus ...

Sankey diagram illustrating the inferred functions of TE-proximal genes. The width of connections between each vertical block represents the gene count, delineating GO term classifications associated ...

Ancient viruses are embedded everywhere in the human genome. Estimates range, but it's thought that about eight percent of the human genome could be made up of these ancient retroviruses, which are ...

Heterochromatin, sometimes known as the “dark side of the genome,” is a poorly studied fraction of DNA that makes up about half of our genetic material. For more than 50 years scientists have puzzled ...