Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life. Metabolites are simple compounds generated during life-sustaining chemical ...

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages ...

The study-led by Rose Glass, PhD, and Nana Matoba, PhD-was conducted using meticulously grown stem cells that mimic the earliest stages of human brain development in a dish. The findings, which were ...