Background. A 61-year-old man presented with shortness of breath and chest pain on exertion. He had been diagnosed as having hiatus hernia 2 years previously and was taking proton-pump inhibitors as ...

Adolescent patients with obstructive hypertrophic cardiomyopathy (HCM) who received the drug mavacamten saw a significant ...

Due to chest pain of unknown origin, a 59-year-old woman with a history of hypertension, hyperlipidemia, and smoking underwent coronary computed tomography angiography (CCTA) following negative ...

The cardiac myosin inhibitor gets a big win in the SCOUT-HCM trial ...

Unique in its focus on adolescents, the trial shows the cardiac myosin inhibitor safely reduces LVOT in the pediatric ...

HRS-1893 (also known as BHB-1893) is a selective, small-molecule, cardiac myosin inhibitor engineered to improve heart performance in patients with HCM. By modulating cardiac contractility, HRS-1893 ...

Please provide your email address to receive an email when new articles are posted on . Two weeks of metoprolol improved left ventricular outflow tract gradients, symptoms and quality of life compared ...

Fabry disease (FD) is a rare X-linked lysosomal storage disorder caused by mutations in the galactosidase α (GLA) gene, leading to a deficiency in or absence of α-galactosidase A activity. The ...

In patients with hypertrophic cardiomyopathy and obstruction of the left ventricular outflow tract, nonsurgical reduction of the septum is a treatment option when medical therapy has failed. We ...

Approximately a quarter of patients with hypertrophic cardiomyopathy (HCM) have left ventricular outflow tract obstruction (LVOTO) and this has been associated with poor outcome. The association ...

TCT 1521: Transcatheter Aortic Valve Replacement in a Patient With Durable Ventricular Assist Device and Quadricuspid Aortic Valve With Severe Insufficiency Receive the the latest news, research, and ...