Urinary afamin and an immune biomarker model both show potential for distinguishing lupus nephritis. Urinary afamin, circulating immune cell ratios, and antimitochondrial antibodies each demonstrate ...

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by ...

Lupkynis is a medicine that is used for a specific kidney disease called lupus nephritis. Lupus nephritis is a kidney condition that affects people with systemic lupus erythematosus (SLE). SLE is an ...

Lupus is a type of autoimmune disease. In an autoimmune disease, something goes wrong in the body’s immune system, causing it to harm healthy organs, tissues, and cells. “Auto” means “self” — so if ...

The body's immune reaction to increased levels of a toxic molecule, part of a bacterial species in the human gut, may reveal who is most at risk of developing lupus nephritis, according to a new study ...

C3 glomerulopathy (C3G) and immune complex membranoproliferative glomerulonephritis (IC-MPGN) are rare and progressive kidney diseases, caused by problems in the immune system. They are two distinct ...

In a clinical trial of 7 patients, anti-BCMA only CAR-T cell treated patients with refractory lupus nephritis safely and effectively. Anti-B cell maturation antigen (BCMA)-targeting chimeric antigen ...

New research is shedding light on the biological mechanisms that may help explain why systemic lupus erthyematosus (SLE) and ...

On the heels of last week’s lupus nephritis nod from the FDA, Roche’s Gazyva is proving once again that it still has new tricks despite its 12 years on the market—and not just in its original oncology ...

C3 glomerulopathy (C3G) and immune complex membranoproliferative glomerulonephritis (IC-MPGN) are rare kidney conditions caused by an overactive complement system, part of the immune system. C3G ...