Chromosomal instability in oesophageal cancer drives immunosuppression and poor outcomes through altered immune signalling ...

As it transitions from a discovery- to a clinical-stage biotech, Volastra Therapeutics is bringing longtime adviser Samuel Bakhoum, M.D., Ph.D., on board as its chief scientific officer. Bakhoum is a ...

Cancer researchers have long treated genetic chaos and epigenetic rewiring as separate engines of disease, two parallel hallmarks that help tumors grow, spread, and resist treatment. Now a new wave of ...

Accent Therapeutics, a clinical-stage biopharmaceutical company pioneering novel small molecule precision cancer therapies, today presented preclinical data supporting its potentially best-in-class ...

B-cell acute lymphoblastic leukaemia is the most common form of childhood cancer. In this type of cancer, which affects blood cells, one of the most common abnormalities is the presence of cells with ...

Quality of life and lifestyle changes during and after therapy in women with endometrial cancer: A global study of 1,066 patients (NOGGO, ENGOT, GCIG, ENGAGe-IMPROVE ...

Left: Normal cell division with the chromosomes (blue) lined up and ready to be pulled into two separate daughter cells by the two centrosomes (green). Right: In faulty cell division, too many ...

Triple negative breast cancer (TNBC) is one of the most aggressive and hardest forms of breast cancer to treat, but a new study led by Weill Cornell Medicine suggests a surprising way to stop it from ...

Validation of large chromosomal segment deletions by chromosome painting. (a, b) FISH assays of the chr2 barcode probes and chr2 painting probes on metaphase chromosomes prepared from LeiTing. The ...